The study, titled "Efficacy and Safety of Three Topical Therapeutic Regimens Containing 5% Minoxidil, 0.064% Betamethasone, and Castor-Jojoba Oils for Alopecia Areata: A Multicenter Observational Study," was authored by Dr. Basma Damiri and Dr. Munther Ardah from the Faculty of Medicine and Allied Medical Sciences, and Dr. Sari Taha from the Global Health Institute at An-Najah. The study was conducted in collaboration with Dr. Manal Ardah, Dr. Amir Abadi, Dr. Walaa Abdeljawad, Dr. Emad Khatib, and Dr. Shorouq Jaber.

This multicenter observational study evaluated 278 patients using a dermatoscopic imaging tool (trichoscope) during three follow-up visits to assess hair regrowth, patient satisfaction, and treatment adherence (on a 10-point scale). The study compared three treatment protocols: Topical betamethasone alone, Betamethasone with 5% minoxidil, and Betamethasone with a blend of castor and jojoba oils.

Results demonstrated that the combination of minoxidil and betamethasone was the most effective, showing the highest hair regrowth rate (83.2%), greatest patient satisfaction, and fastest onset of improvement, outperforming both the monotherapy and the herbal blend treatments.

The researchers highlighted the clinical significance of these findings and their potential to inform the development of effective and safe treatment protocols for patients with alopecia areata. They also recommended conducting future randomized clinical trials to build upon the evidence generated by this observational study.

This scientific contribution reflects An-Najah’s and the Global Health Institute’s growing impact in clinical and applied medical research at the regional and international levels, underscoring their commitment to evidence-based medicine and improving patient quality of life.

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